Nexgard Combo is an anti-parasitic monthly spot-on treatment used to treat both internal and external parasites in cats. Nexgard combo treats external parasites like fleas, ticks, ear mites or skin mites, and internal intestinal parasites like hookworms, tapeworms and roundworms. It can also be used to treat lungworms that infect the bladder. Nexgard combo also prevents heartworms and can be used as part of the management of flea allergy dermatitis.
Nexgard Combo contains three main ingredients, Esafoxolaner, Eprinomectin and Praziquantel, which work in different ways to kill external and internal parasites.
Esafoxolaner, being an ectoparasiticide, works on the external parasites that live on the fur of the cat. It interrupts the neurotransmission of the external parasites, resulting in uncontrolled activity of the parasite’s nervous system and death.
The other two ingredients, Eprinomectin and Praziquantel, are endoparasiticides. They work on the internal parasites that live inside the cat’s body. Prazoquantel kills tapeworms by damaging their cell membranes, and Eprinomectin kills roundworms by paralyzing their nervous systems.
Note: NexGard Combo is safe to use on cats older than 8 weeks of age.
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Suitable for cats and kittens 8 weeks and older, weighing 1.8 lbs or greater, Nexgard Combo is the innovative cat parasitic protection. Click 'read more' to discover why you should use Nexgard Combo topical solution.
A broad-spectrum topical solution that protects against a range of internal & external parasites for one month.
Comes in an easy-to-apply plunger applicator, making administration simple and hassle-free.
Combines 3 powerful ingredients (esafoxolaner, eprinomectin & praziquantel) to deliver one-and-done protection.
Kills adult fleas before they can lay eggs, treats & prevents flea infestations and treats & controls black-legged tick and lone star tick infestations.
Indicated for the prevention of heartworm disease caused by Dirofilaria immitis.
Treats & controls infections of adult and immature roundworms, hookworms and tapeworms.
Administering Nexgard Combo on your cat is simple and hassle-free. Follow these 6 easy steps to unleash the power of this powerful 3-in-1 formula.
Nexgard Combo contains a triple-action formula including esafoxolaner (specially designed for cats), eprinomectin and praziquantel. After administration, the topical formula is spread throughout the cat's body and the active ingredients are absorbed into the systemic circulation as shown in the image.
The formula impacts ectoparasites such as fleas and ticks as soon as these parasites take a blood meal. At the same time, it acts on endoparasites through oral absorption or transcuticular/integument absorption, according to the worm species.
Inhibits ligand-gated chloride channels; blocks pre-& post-synaptic transfer of chloride ions causing uncontrolled nervous system activity & death of acarines.
Increases the permeability of the cell membrane to chloride ions, triggering hyperpolarization of nerve or muscle cells leading to paralysis & death of the parasite.
Not exactly known. Treated tapeworms experience muscular paralysis together with a rapid influx of calcium ions & the disruption of the tegument.
The following frequently asked questions (FAQs) may help answer a few queries about Nexgard Combo for Cats.
Yes, Nexgard Combo comes with wide safety margins. It is safe for use in kittens and cats from 8 weeks of age, weighing at least 1.8 lbs including heartworm-positive cats.
The safe use of Nexgard Combo has not been evaluated in breeding, pregnant, or lactating cats.
Yes, even an indoor cat is susceptible to parasitic infestations. Fleas and ticks can hitchhike in your house on people or other pets and infest an indoor cat. Other pets or animals including cockroaches or rodents can get infected with intestinal worms that can be transmitted to the indoor cat. Plus, infected mosquitoes can transmit the deadly heartworm disease to the cat that doesn't go outside.
It is likely you are seeing newly attached fleas on your cat, which get attached to your cat when the cat moves around flea-infested areas and this shall continue depending on the environmental conditions. Nexgard Combo shall kill these fleas soon before they can reproduce. It is, therefore, necessary to provide your cats with a flea treatment throughout the year without interruption.
The use of Nexgard Combo together with other treatments, including vaccines, antibiotics, analgesics, etc., does not affect its efficacy. For specific concurrent use of Nexgard Combo, please speak to your vet.
Yes, the treatment with Nexgard Combo can be started any time during the year. To prevent heartworm disease, it is recommended to administer Nexgard Combo once every month, at least 3 months after the last exposure to mosquitoes.
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